Objective:To explore the surgical treatment and timing of the elderly patients with acute cholecystitis. Methods:The clinical data of 458 aged cases with acute cholecystitis from January 2000 to August 2007 in the First Affiliated Hospital of China Medical University were analized retrospectively. Results:The nonsurgical operation treatment cases’ mortality is 3.9%,average hospitalization time is 16.9d,but the correspond number of surgical operation treatment cases is 1.0% and 11.3d. Conclusion:Acute cholecystitis of the elderly patients progress rapidly treatment is difficult,risk is high,only if more attention be paid to command time and technical skill of surgical treatment,early surgical treatment can reduce mortality and reduce hospitalization time significantly.It is safe and feasible.