Objective:To explore the preoperative management of 306 advanced age patients combined cardiovascular disease with colorectal cancer. Methods:The clinical data of 306 cases over 70 years old of colorectal cancer combined cardiovascular disease admitted between January 2004 to December 2006 were evaluated and classified with ACC/AHA 2001 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery to 3 risk levels and the preoperative management was analyzed retrospectively. Results:20 cases in high level,70 cases in intermediate level and 216 cases in low level. Postoperative complications included:stage 3 hypertension (22cases),congestive heart failure(10 cases),angina pectoris(3 cases),acute myocardial infarction(1 case),cardiac arrhythmia(102 cases),wound dehiscence(3 cases),pneumonia(34 cases),anastomotic leakage(6 cases),stress ulcer(8 cases),4 cases died in postoperative period. Conclusion:The cardiovascular disease increase the risk of surgical procedures of advanced age patients with colorectal cancer,but complete assessment of the patient’s general health and intensive perioperative management of the cardiovascular diseases can increase the success rate of operation and decrease the operative mortality and incidence of complication.