Objective:Evaluate the value of technique of spleen subpedicle severance for splenectomy in portal hypertension patients. Methods:Compare stay time,operation time,blood loss volume,incidence rate of complication between spleen subpedicle group and control group in portal hypertension patients with splenectomy and Pericardiac devascularization.and analysis the relationship between complication and spleen size. Results:The incidence rate of spleen fever,pancreas leakage and stay time are higher in control group than in test group.The operation time and blood loss volume are no significantly different in two groups.Spleen size in patients with spleen fever or pancreas leakage is thicker than in patients without spleen fever or pancreas leakage. Conclusion:The technique of spleen subpedicle severance can decrease incidence rate of spleen fever,pancreas leakage and shorten stay time in portal hypertension patients with splenectomy and Pericardiac devascularization.It is a value operation technique especially for patients with large spleen.