The right posterior lobe of the liver accounts for approximately 1/3 of the total liver volume, with a complex and highly variable ductal anatomy involving the first caudal branch arising from the main trunk of the posterior branch of the portal vein, the branching patterns of the tributaries of the right hepatic vein, the anatomical characteristics of the inferior right hepatic vein, and the anatomical adjacency of the right posterior lobe; these factors collectively increase the difficulty of anatomical identification and surgical manipulation. Through rational preoperative planning and intraoperative navigation, surgical risks can be effectively reduced, resection precision can be maximized, and liver function can be preserved. Laparoscopic precise resection of the right posterior region of the liver offers new insight into function-preserving and holds potential value for optimizing individualized treatment strategies and improving patient prognosis.