关键词: 胆囊癌, 早期诊断, 综合治疗, 外科手术, 新辅助治疗

Abstract: Several key issues that should be paid attention to in the comprehensive diagnosis and treatment of gallbladder cancer        LIU Ying-bin, CHEN Wei. Department of Biliary-Pancreatic Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
Corresponding author: LIU Ying-bin, E-mail：laoniulyb@163.com
Abstract    Gallbladder carcinoma has a high degree of malignancy and poor prognosis. Improving the sensitivity and accuracy of imaging diagnosis, and discovering specific molecular diagnostic targets is helpful for early diagnosis. Surgical treatment is still the most important treatment for this disease, and accurate preoperative evaluation is the prerequisite for successful surgical treatment. There are still some controversies in laparoscopic radical resection, lymph node dissection, revascularization, and multi-organ resection. Nerve invasion may be a risk factor for short-term recurrence after surgery and should be highly concerned. Neoadjuvant therapy gives full play to the effects of chemotherapy, targeted therapy, and immune therapy on tumor cells, which can benefit some patients with advanced gallbladder cancer.

Key words: gallbladder cancer, early diagnosis, comprehensive treatment, surgical procedures, neoadjuvant therapy