中国实用外科杂志

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EST治疗中Oddi括约肌功能的保护及其意义

陆新良a梁廷波b   

  1. 浙江大学医学院附属第二医院 浙江省胰腺病研究重点实验室  a.消化内科  b.肝胆胰外科,浙江杭州 310009
  • 出版日期:2017-08-01 发布日期:2017-07-25

  • Online:2017-08-01 Published:2017-07-25

摘要:

Oddi括约肌结构精巧,精细控制胆汁和胰液的排泄,有效防止十二指肠内容物反流和细菌逆行感染。内镜乳头括约肌切开术(EST)破坏Oddi括约肌完整性,导致括约肌松弛或狭窄,使其部分或者完全失去原有的生理功能。因此,须严格掌握EST适应证,尽可能保留括约肌功能,为病人提供更合理与规范化的治疗策略。

关键词: Oddi括约肌, 内镜乳头括约肌切开术, 内镜逆行胰胆管造影

Abstract:

Protection of Oddi sphincter function and its significance in endoscopic sphincterotomy        LU Xin-liang*,LIANG Ting-bo. *Department of Gastroenterology, the Second Affiliated Hospital, Zhejiang University School of Medicine; Key Laboratory of Pancreatic Diseases of Zhejiang Province, Hangzhou 310009, China.
Corresponding author: LIANG Ting-bo, E-mail:liangtingbo@
zju.edu.cn
Abstract    The sphincter of Oddi is a neuromuscular structure located at the junction of the bile and pancreatic ducts with the duodenum. The primary functions of the sphincter of Oddi are to regulate the delivery of bile and pancreatic juice into the duodenum and to prevent the reflux of duodenal contents restrograde infection. EST damage the integrity of the Oddi sphincter, leading to sphincter relaxation or stenosis, causing partial or complete loss of the original physiological function of the Oddi sphincter. Therefore, surgeons should strictly control the indications of EST, retain the sphincter function as far as possible, so as to provide patients with more reasonable and standardized treatment strategy.

Key words: sphincter of Oddi, endoscopic sphincterotomy, endoscopic retrograde cholangiopancreatography