完全性腹腔镜远端胃癌根治术与腹腔镜辅助远端胃癌根治术疗效对比Meta分析
王君辅,谢 勇,胡 林,李红浪
中国实用外科杂志 ›› 2014, Vol. 34 ›› Issue (04) : 351-355.
完全性腹腔镜远端胃癌根治术与腹腔镜辅助远端胃癌根治术疗效对比Meta分析
目的 比较完全性腹腔镜远端胃癌根治术(TLDG)与腹腔镜辅助远端胃癌根治术(LADG)治疗胃癌的效果。方法 通过PubMed、EMBASE、Medline、中国期刊全文数据库、万方数据等对2008-2013年有关TLDG与LADG的回顾性分析文献进行定量综合分析,采用RevMan 5.1软件用固定效应模型进行Meta分析。结果 按纳入标准,共6篇文献纳入研究。Meta分析结果显示:TLDG术中出血量较LADG少31.26 mL(P=0.005);TLDG组术后止痛剂平均使用次数较LADG组少0.38次(P=0.04);TLDG术后1 d血清C反应蛋白水平较LADG组降低9.3×10-4mg/L(P=0.03);手术时间、住院时间、首次排气时间及术后并发症两组差异均无统计学意义(P>0.05)。结论 根据目前的数据分析无法证明TLDG优于LADG,可根据病人具体情况及外科医生的偏好来选择。
Totally laparoscopic distal gastrectomy and laparoscopic-assisted distal gastrectomy:A Meta-analysis of efficacy comparation WANG Jun-fu, XIE Yong, HU Lin, et al. Department of Gastrointestinal Surgery, the Second Affiliated Hospital of Nanchang University, Nanchang330006, China
Corresponding author: LI Hong-lang, E-mail: lihonglang6802@163.com
Abstract Objective To compare the effect difference of totally laparoscopic distal gastrectomy(TLDG) and laparoscopic-assisted distal gastrectomy (LADG). Methods Randomized controlled trial reports on TLDG and LADG from 2008 to 2013 were collected from PubMed,EMBASE,Medline,China National Knowledge Infrastructure (CNKI) and Wanfang databases. RevMan 5.1 software was used for data analysis. Results According to the included criteria, 6 clinical trials were selected finally. Meta-analysis showed that: blood loss in TLDG group was 31.26mL less than that in LADG group (P=0.005); The frequency of analgesic usage in the TLDG group was 0.38 times lower than LADG group (P=0.04); serum C-reactive protein levels decreased 0.93g/L after one day in TLDG group (P=0.03). There was no statistical difference in operation time, hospital stay, postoperative first exhaust time and complications between the two groups(P>0.05). Conclusion It could not demonstrate the clinical superiority of TLDG over LADG based on the current data. The surgical method may be selected according to patients’ conditions and the surgeon’s preference.
完全性腹腔镜远端胃癌根治术 / 腹腔镜辅助下远端胃癌根治术 / Meta分析
totally laparoscopic distal gastrectomy(TLDG) / laparoscopic-assisted distal gastrectomy(LADG) / meta-analysis
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