关键词: 胰腺肿瘤, 胰十二指肠切除术, 胰腺空肠吻合

Abstract: The history and recent advances of pancreaticojejunostomy        YAN Wei-kang，LIU Ying-bin. Department of Biliary-Pancreatic Surgery，Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine；Shanghai Cancer Institute，State Key Laboratory of Oncogenes and Related Genes；Shanghai Key Laboratory of Biliary Tract Disease；Shanghai Research Center of Biliary Tract Disease，Shanghai 200127，China 
Corresponding author：LIU Ying-bin，E-mail：laoniulyb@163.com
Abstract    Originated from pancreaticoduodenostomy，pancreaticojejunostomy can be subdivided into three parts including end-to-end, end-to-side and duct-to-mucosa after more than a hundred years of development. As one of the most influential factors of the fatal pancreatic fistula，the method of pancreaticojejunostomy has been studied and improved in recent years. The newly invented anastomosis methods，such as purse-string suturing technique，binding pancreaticojejunostomy，"U"-suture technique，shark mouth pancreaticojejunostomy，Blumgart anastomosis, and single-stitch pancreatic duct suture，are worth introducing here because of their inspiration，innovation and practicality.At present, there is still insufficient evidence to indicate which anastomosis technique has a clear advantage in preventing pancreatic fistula. Regardless of open surgery or laparoscopic surgery, the current consensus recommends that the operator should choose a more skilled technique based on his own experience, so as to improve the quality of the anastomosis. The mechanism of pancreatic fistula needs to be further studied to guide the reconstruction of pancreatic stump and avoid the occurrence of pancreatic fistula.

Key words: pancreatic neoplasms, pancreaticoduodenectomy, pancreatojejunostomy