围手术期脓毒性休克液体治疗一直是外科临床关注的热点。围手术期脓毒性休克液体治疗的核心目标是早期目标指导治疗，目标导向性液体治疗逐步成为普遍认可的液体治疗策略。注意不同复苏液体种类（晶体和胶体）的差异，尤其是颇受关注的羟乙基淀粉。应关注脓毒性休克液体治疗以外的药物治疗，如血管活性药、心肌正性肌力药和糖皮质激素。

The basic principles of fluid therapy in perioperative patients with septic shock        GUAN Xiang-dong，HUANG Shun-wei. Surgical Intensive Care Unit，the First Affiliated Hospital，Sun Yat-sen University，Guangzhou 510080，China
Corresponding author：GUAN Xiang-dong，E-mail：carlg@163.net
Abstract    Fluid therapy in perioperative patients with septic shock has been the focus of attention. Early goal-directed therapy (EGDT) remains the core in fluid therapy in perioperative patients. Goal-directed fluid therapy (GDT) has gradually become widely recognized strategy. The different types of fluid (crystalloid and colloid) should be concerned，especially hydroxyethyl starch (HES). Besides some other medication should be concerned such as vasoactive drug, myocardium inotropic agent and glucocorticoids.