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癌性肠梗阻个体化治疗策略
周总光a,b,尹 源 a,于永扬a,陈志新a,胡建昆a,王自强a,伍晓汀a,卢铀b,c,莫显明b
中国实用外科杂志 ›› 2014, Vol. 34 ›› Issue (01) : 41-43.
PDF(404 KB)
PDF(404 KB)
癌性肠梗阻个体化治疗策略
癌性肠梗阻的确切定义应涵盖由胃肠道原发肿瘤、系膜或盆腔肿瘤及其复发转移瘤导致的完全或不完全肠道梗阻。随着我国腹部恶性肿瘤的发病率逐年升高,癌性肠梗阻也成为普外科最常见的外科急诊和处理棘手的临床难题。 由于梗阻部位及程度、是否伴复发转移、全身状况好坏、是否合并基础疾病等差异甚大,治疗上既要解除梗阻,又要兼顾肿瘤治疗,让病人最大获益;这考验着临床医生的肿瘤专科技能、知识更新、多学科协作及综合实力。专业技术水平不同的外科医生处理临床分期、分级近似的癌性肠梗阻,可获得预后完全不同的结果。应根据癌性肠梗阻临床特点、临床实践经验以及当今腹部恶性肿瘤治疗原则,探讨癌性肠梗阻病人的个体化综合治疗策略。
Personalized management strategies for malignant bowel obstruction ZHOU Zong-guang*, YIN Yuan, YU Yong-yang, et al. *Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China
Corresponding author: ZHOU Zong-guang, E-mail:zhou767@163.com
Abstract With the incidence of abdominal malignancies keeping to increase, malignant bowel obstruction, including complete or incomplete bowel obstruction caused by primary abdominal malignancies of gastrointestinal tract,mesentery and pelvis, and recurrent or metastatic tumor, has become the most common and troublesome clinical problems. As the conditions of the disease including the location and severity of obstruction, stage of the malignancy, and the general condition and comorbidity of the patients vary greatly, it is challenges for the surgeons that the clinical skills and knowledge updating of physicians, and multi-discipline team(MDT)cooperation, suggesting that patients would benefit from strategy treatment plan considering both the relieving obstruction and the managing tumor at the same time. In fact, different surgeons on the management of malignant bowel obstruction may produce completely different prognosis,depending on technical specification and surgical experience of the surgeons. The purpose of this article is to try to summarize a personalized management strategy for patients with malignant bowel obstruction based on the clinical features of the disease in China, the treatment principle of abdominal malignancies and clinical practice experience.
malignant bowl obstruction / personalized management / standardized operation
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