胃癌癌前病变（gastric precancerous lesion，GPL）是病理学概念，指已具备恶性转化能力的胃黏膜病理改变，目前，胃黏膜肠化生和异型增生是较为公认的GPL。GPL早期诊断较为困难，内镜检查技术的进步和生物学指标的发现有望提高GPL诊断率。GPL的处理原则尚未达成共识，在根除幽门螺杆菌（HP）的基础上进行药物治疗、内镜治疗或者腹腔镜手术治疗是值得推荐的治疗模式。进一步深入探索GPL的发生和逆转机制，寻找阻断GPL发展成为胃癌的有效途径仍是今后研究的方向。

Diagnosis and treatment for gastric precancerous lesions           HUANG Chang-ming，LU Jun. Department of Gastric Surgery, Fujian Medical University Union Hospital，Fuzhou 350001，China
Corresponding  author ：HUANG Chang-ming，E-mail：hcmlr2002@163.com
Abstract    Gastric Precancerous Lesion（GPL）is a concept of pathology，refers to the gastric mucosa pathological changes which have the ability to malignant transformation. Current knowledge indicates that intestinal metaplasia and dysplasia are recognized as GPL. Early effective treatments for this condition are not currently available. The progress of endoscopic examination technology and discovery of new biological indicator are expected to improve the GPL diagnostic rate. The principle of treatment for GPL has not yet reached a consensus. Drug therapy, endoscopic therapy or laparoscopic surgical treatment on the basis of the eradication of  helicobacter pylori (HP) are recommended. Further exploring the accurate mechanism and effective pathway of blocking GPL become gastric cancer is still the future research direction.