胰腺浆液性囊腺瘤可为单囊型、微囊型及实性型等，内覆富于糖原的透明立方上皮，其恶变的可能性很小。因此，只有在引起症状或难以与黏液性肿瘤鉴别时才行手术治疗。黏液性囊性肿瘤和导管内黏液性乳头状肿瘤均可根据形态学分为低级别异型性、中级别异型性、高级别异型性及伴有浸润性癌，二者的主要区别为是否与胰腺导管相通，且黏液性囊性肿瘤常有卵巢样间质；实性假乳头瘤是胰腺具有独特形态学和免疫表型的肿瘤，虽然为低度恶性肿瘤，大部分表现为良性经过；腺泡细胞囊腺瘤与胰腺浆液性囊腺瘤一样，绝大多数为良性，仅有个别恶性病例的报道；胰腺的杂类囊性肿瘤主要有成熟性畸胎瘤、淋巴上皮囊肿、囊性淋巴管瘤及多囊性腺瘤样错构瘤，均为良性肿瘤。应特别注意原发的胰腺实性肿瘤继发囊性变，可能与一些胰腺原发囊性肿瘤相混淆。

Classification and pathology features of pancreatic cystic neoplasmas        LU Zhao-hui,CHEN Jie. Department of Pathology, Peking Union Medical College Hospital , Peking Union Medical College, Chinese Academy of Medical Science,Beijing100730,China
Corresponding author: CHEN Jie,E-mail:xhblk@163.com
Abstract    Serous cystadenoma consists of oligocyst, multiple microcysts or solid acinars lined by a glycogen-rich cuboidal epithelium. Based on the low risk of malignancy of SCA, surgical resection should only be considered when the cysts are causing symptoms or when differentiation from a mucinous cystic neoplasm with concerning features is not possible. Mucinous cystic neoplasm and Intraductal papillary mucinous neoplasm can all be classified into 4 catograies: low-grade dysplasia, moderate dysplasia, high-grade dysplasia and with invasive carcinoma, while the major difference between them is whether the cysts are communicated to the duct of pancreas and most MCNs develop ovarian-like stroma. Solid-pseudopapillary tumor of pancreas is a neoplasm with distinctive morphology and immunophenotype, most of them are benign although labeled with low malignancies. Most acinar cell cystadenomas are benign, just like the serous cystadenoma, only very rare cases reported to be malignant. Other miscellaneous cystic tumors consist mature teratoma, lymphoepithelial cyst, cystic lymphangioma and Multicystic adenomatoid pancreatic hamartoma, all follow a benign course. Attentions should be paid to some primary solid pancreatic tumors with cystic transformation, which might be confused with some primary cystic neoplasms.