目的    探讨自体大隐静脉移植治疗下肢缺血性疾病临床疗效。方法    自2010 年 10月至 2012 年 4月新疆医科大学第一附属医院血管外科对 32 例病人（男27例，女5例）的32条由动脉硬化闭塞症、血栓闭塞性血管炎、外伤导致动脉损伤致下肢动脉节段性闭塞有缺血表现的FontaineⅢ、Ⅳ期下肢，分别应用自体大隐静脉予以大隐静脉翻转后行动脉旁路移植术、动脉内膜剥脱+大隐静脉补片动脉成形术治疗。 结果    32例病人患肢症状不同程度好转，生活质量明显改善。术后即静息痛消失，术后1~2个月足部溃疡愈合，术后随访 2~17个月，大多数病人间歇性跛行明显好转，无截肢，保肢率100%。 结论    根据病变部位与程度应用自体大隐静脉手术是治疗下肢缺血性疾病的廉价而有效的方法。

Clinical application of autogenous sapheneous vein in lower limb ischemic disease        AIZEZI Abudureyimu, TIAN Ye, SAILIKE Magaoweiya, et al. Department of Digestive & Vascular Surgery, First Hospital of Xinjiang Medical University, Urumqi 830054, China
Corresponding author: WEN Hao, E-mail:dr.wenhao@163.com
Abstract    Objective    To explore the clinical application and effectiveness of autogenous sapheneous vein in the treatment of lower limb ischemic disease. Methods    Thirty two arteries of 32 patients (27 male, 5 female) with arteriosclerosis obliterans, thromboangitis obliterans and Fontaine stage Ⅲ and Ⅳ lower limb with ischemic manifestation of segmental artery occlusion disorder caused by arterial injury were operated by artery bypass grafting after with inside-out autogenous great saphenous vein graft, endarterectomy with artery angioplasty by using great saphenous vein patch from October 2010 to April 2012 in Department of Vascular Surgery, First Hospital of Xinjiang Medical University. Results    The ischemic symptoms and life quality of 32 patients were improved to various degree. Resting pain was disappeared post-operatively and the foot ulcer was cured at 1-2 month. The mean follow-up was 9.5 months (2-17 months). Intermittent claudication in most patients was improved significantly. There is no amputation performed with limb salvage rate 100%. Conclusion    The clinical application of autogenous sapheneous vein in the treatment of lower limb ischemic disease according to pathological position and degree is a cheap, effective method.