炎性乳腺癌是一种具有高侵袭性的特殊类型乳腺癌，疾病进展迅速，预后较差。其诊断主要依据特征性的临床表现及病理确诊。目前，整合新辅助化疗、手术、放疗、内分泌治疗以及靶向治疗是炎性乳腺癌最佳的综合治疗模式。分子病理机制的研究，将为炎性乳腺癌未来的治疗提供一种新的方式。

Diagnosis and therapeutic principle of inflammatory breast cancer        GAO Wei-qi, SHEN Kun-wei. Comprehensive Breast Health Center, Shanghai Ruijin Hospital, Shanghai Jiao Tong University, Shanghai 200025, China
Corresponding author：SHEN Kun-wei，E-mail：kwshen@medmail.com.cn  
Abstract    Inflammatory breast cancer (IBC) is an aggressive manifestation of primary breast cancer that progresses rapidly and carries a very grim prognosis. Diagnosis of IBC is made on the basis of its specific clinical characteristics as well as histopathologic verification of carcinoma. The optimal therapeutic strategy for IBC is to integrate different modalities consisting of neoadjuvant chemotherapy, surgery, radiotherapy, endocrine therapy and targeted therapy. The research of IBC’s molecular pathogenesis might provide potential therapeutic approaches.