因病理和临床医生的关注点不同，对特殊类型乳腺癌的定义理解也不尽相同。世界卫生组织（WHO）于2012年发布的“肿瘤组织学和遗传学分类”（第4版）中介绍了《乳腺肿瘤组织学分类》的变化，从外科临床工作的角度将特殊类型乳腺癌进行分类。提出：对特殊类型乳腺癌应加强临床总结；对特殊情况乳腺癌在临床治疗上应区别对待。分子分型的提出对非特殊型浸润性乳腺癌组织学分型的意义提出了挑战。特殊类型乳腺癌外科的循证研究尚显不足，需进行更广泛的研究和实践。

Classification of special breast cancer and the principles in diagnosis and treatment        JIANG Jun. Breast Disease Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
Abstract    From the aspect of pathology and the viewpoint of clinicians, the definitions of “special breast cancer” differ. This paper briefly introduced the “WHO classification of tumors of the breast” in “Histological and genetic classification of tumors” released by WHO in 2012, and classified the special breast cancers based on clinical experience. The main conclusions were listed as follows: it is necessary to summarize the clinical classification of special types of breast cancer; the treatment for the unusual conditions should be individualized. The molecular subtyping gives a challenge to the histological classification of "non-special type of invasive breast cancer”. All in all, the evidence-based research for surgical treatment against “special breast cancer” is insufficient, which requires more extensive studies.