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经脐单孔腹腔镜与传统腹腔镜胆囊切除术安全性Meta 分析

王晔飞1,沈    艾1,刘    波2,王洪林1   

  1. 1重庆医科大学附属第一医院肝胆外科,重庆400016;2成都市郫县人民医院,四川成都611730
  • 发布日期:2012-11-29

  • Published:2012-11-29

摘要:

目的    探讨经脐单孔腹腔镜胆囊切除术(SILC)的安全性。 方法    计算机检索 Cochrane 图书馆(2011年第1期) 、PubMed(1978-2011 年)、 EMBase(1978-2011年)、CNKI (1978-2011年)有关SILC与传统腹腔镜胆囊切除术(CLC)的随机对照试验。按照入选标准,有8项临床试验纳入本研究,由2名作者各自独立地对入选研究中有关试验设计、研究对象的特征、研究结果等内容进行摘录,并用RevMan5.1软件进行分析。 结果    与CLC相比较,SILC除手术时间延长外[MD=8.03,95%CI(6.02,10.03),P<0.01],术中出血量[MD=-2.41,95%可信区间为(-5.66,0.83),P=0.15]、术后住院时间[SMD=0.15,95%CI(-0.06,0.37),P=0.16]及并发症的发生率[RR=1.21, 95%可信区间为(0.53,2.78),P=0.69]差异均无统计学意义。结论    对于有条件的医院,经过严格筛选病人,SILC是一种安全有效的手术方式,尤其适用于对美容有强烈要求的病人。

关键词: 经脐单孔腹腔镜胆囊切除术, 腹腔镜胆囊切除术, Meta分析

Abstract:

Safety of transumbilical single-incision laparoscopic cholecystectomy versus conventional laparoscopic holecystectomy: a meta analysis        WANG Ye-fei*, SHEN Ai , LIU Bo,et al.*Department of Hepatobiliary Surgery,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China
Corresponding author: WANG Hong-lin, E- mail: whlcqykd@163.com
Abstract    Objective    To evaluate the safety of transumbilical single-incision laparoscopic cholecystectomy. Methods Cochrane library (No.1 2011), PubMed (1978-2011), EMBase (1978-2011) and CNKI (1978-2011) were searched for randomized controlled trials on the efficacy of transumbilical single-incision laparoscopic cholecystectomy (SILC) versus conventional laparoscopic holecystectomy (CLC) for the treatment of benign gallbladder disease. According to the inclusion criteria, eight studies were selected. Two authors cited the details about the designs of the trials,identities of the participants and the outcomes from the studies included independently. The data were analyzed by Revman 5.1 software. Results    Operating time in the SILS group was longer than that in the CLC group signi?cantly (weighted mean difference =8.03,95% confidence interval(6.02,10.03),P<0.01). There was no signi?cant difference in the introoperative blood loss[weighted mean difference=-2.41,95% confidence interval(-5.66,0.83),P=0.15], postoperative hospital stay[weighted=0.15,95% confidence interval(-0.06,0.37), P=0.16] and the postoperative complications incidence[relative risk=1.21, 95% confidence interval(0.53,2.78),P=0.69] between the two groups. Conclusion    SILC is a safe procedure for the treatment of uncomplicated gallstone disease, especially for cosmetic purpose.

Key words: transumbilical single-incision laparoscopic cholecystectomy, laparoscopic cholecystectomy, Meta-analysis