中国实用外科杂志 ›› 2012, Vol. 32 ›› Issue (09): 693-696.

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我国结直肠癌30年变迁与应对策略

周总光a,b,杨    烈a,b,李    园b,于永扬a,王    存a,b,胡建昆a,b,卢    铀b,c,莫显明b   

  1. 四川大学华西医院  a.胃肠外科中心;b.生物治疗国家重点实验室;c.肿瘤科,四川成都610041
  • 出版日期:2012-09-01 发布日期:2012-08-29

  • Online:2012-09-01 Published:2012-08-29

摘要:

30年来,结直肠癌(CRC)的发病率、病死率在世界范围呈现明显的经济、文化和地域特点。总体趋势是:发达国家和地区的CRC发病率及病死率缓慢增高约30%,近10年逐渐降低并趋于稳定,这主要归功于CRC筛查。而我国CRC发病率及病死率则高速增长,达30年前的400%~500%, CRC防治面临巨大考验。我国CRC发病率及病死率高速增长有诸多特定因素,亟待分析阐明。应从专业和科普角度提高全民的CRC防治意识,需将CRC可以预防的理念深入人心;应提高CRC目标人群的筛查率;应定期在CRC高危人群实施结肠镜、乙状结肠镜检查及肛门指检等CRC防治简单而最有效手段。调整防治策略,重心向预防倾斜,势在必行。

关键词: 结直肠癌, 发病率, 病死率, 结直肠癌筛查

Abstract:

The 30 years’ changes of colorectal cancer and the strategies in China        ZHOU Zong-guang*, YANG Lie, LI Yuan, et al. *Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China
Corresponding author: ZHOU Zong-guang, E-mail:zhou767@163.com
Abstract    For 30 years, the incidence and mortality of colorectal cancer (CRC) has displayed obvious economy, culture and region characteristics in the world. Generally, the CRC incidence and mortality slowly increased by about 30% while gradually decreased and tended to stability in recent 10 years in developed countries and regions, largely due to CRC screening. In China, the CRC incidence and mortality have rapidly increased to 400~500% of that before 30 years. The grim situation poses a huge challenge on the strategy and wisdom of CRC control. Multiple specific factors underlie the rapid increasing of the CRC incidence and mortality in China, which should be elucidated urgently. The CRC control awareness should be improved by professional and science popularizing approaches, making the CRC-preventable concept deeply into the mind of people. The CRC screening rate should be increased in target population. The simple and the most effective methods colonoscopy, sigmoscopy and digital rectal examination, should be regularly carried out in the population with high risks of CRC. It is imperative to adjust CRC control strategy and tilt the focus to prevention.

Key words: colorectal cancer, incidence, mortality, colorectal cancer screening