中国实用外科杂志

中国实用外科杂志 ›› 2012, Vol. 32 ›› Issue (01): 31-35.

• 普通外科进展 • 上一篇    下一篇

胃癌分期的变迁——转化医学的重要成果

胡    祥   

  1. 大连医科大学附属第一医院普通外科，辽宁大连110611
  • 出版日期:2012-01-01 发布日期:2011-12-29

  • Online:2012-01-01 Published:2011-12-29

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摘要：

胃癌分期经过半个世纪不断地改进、充实，使其为更精确的判定预后和选择治疗方案提供了科学依据。胃癌分期是胃癌外科进步和国际标准化、规范化治疗的极为重要的平台和基础。胃癌分期的产生、演变是在长期的临床实践、科学研究的基础上形成，特别是转化医学性质的基础和临床研究贯穿于其形成和发展的每个重要时期，尤其是胃癌预后因子T、N的确立，淋巴结转移程度分类基准评价体系的确立，以转移淋巴结个数评价系统为基础的第5版TNM分期的确立，以及2010年日本胃癌规约分期系统与UICC/AJCC TNM分期系统的统一产生的第7版TNM分期体系，无不显示出转化医学理念和转化研究成果的价值与作用。胃癌分期的演变过程是将最新研究成果快速转化为临床医学技术，解决临床问题的转化医学理念的具体体现和实践。

关键词: 胃癌, 分期, 转化医学

Abstract:

The evolution of gastric cancer stage——an important result of translation medicine        HU Xiang. Department of General Surgery, the First Affiliated Hospital, Dalian Medical University, Dalian 110611, China
Abstract    The stage of gastric cancer continually has be improved and enriched in the passed half a century, and which provided a scientific basis for the treatment options of gastric cancer and more accurate to determine the prognosis. Gastric cancer stage is an important platform and infrastructure of international standardization treatment. Stage of gastric cancer have evolved in long-term clinical practice, formed on the basis of scientific research, especially relative translation medicine of basic and clinical medical research through its formation and development of each important period. The establishment evaluation system of gastric cancer prognostic factors T, N , lymph node metastatic degree. 5th TNM which based by the number of metastatic lymph node evaluation system, and based on all of them produced 7th TNM stage system, which all show the concept and value of translation medicine. The evolution of gastric cancer stage is the practice of translation medicine, which made an the latest research results quickly into clinical techniques and resolve the specific clinical problems.

Key words: gastric cancer, stage, translation medicine