中国实用外科杂志 ›› 2011, Vol. 31 ›› Issue (12): 1072-1074.

• 专家论坛 • 上一篇    下一篇

下肢动脉硬化性疾病药物治疗若干问题

管    珩   

  1. 中国医学科学院 北京协和医院血管外科,北京100032
  • 出版日期:2011-12-01 发布日期:2011-11-28

  • Online:2011-12-01 Published:2011-11-28

摘要:

下肢动脉硬化性疾病(lower extremity arterial disease,LEAD)是全身动脉硬化的局部表现,与心脑血管动脉硬化症存在同一病因。症状可从间歇性跛行发展至静息痛最终下肢坏疽截肢,病死率高,是严重影响人类健康的疾病。在多种LEAD治疗方法中,要积极针对动脉硬化的危险因素进行一级预防,药物治疗应治标治本。抗栓治疗可以是LEAD的主要治疗手段,也是手术和介入时必要的辅助治疗。在临床使用LEAD药物时要依据指南更要个体化治疗。

关键词: 下肢动脉硬化性疾病, 药物治疗

Abstract:

Drug therapy for lower extremity arterial disease        GUAN Heng. Department of Vascular Surgery, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing100032,China
Abstract    Lower extremity arterial disease(LEAD) is one of peripheral arterial disease with cardiovascular atherosclerotic disease same cause of partial performance. Lower extremity rest pain, gangrene amputation rate, high mortality and high incidence of serious diseases affect human health. LEAD treatment in a variety of methods should consider risk factors for atherosclerosis therapy for primary prevention and underlying causes actively. Antithrombotic therapy may be the main treatment of LEAD, but also to intervene is necessary in perioperative surgery or LEAD adjuvant therapy. LEAD drugs in clinical use should be based on guidelines but also to individual treatment

Key words: lower extremity arterial disease, drug therapy