尽管外科医生普遍认为保乳手术切缘应该是没有肿瘤细胞的干净切缘，而肿瘤残留将可能增加局部复发概率，甚至增加病死率；但是由于保乳手术在各个国家地区的做法不同及切缘评估方法的差异，至今无保乳手术中有关安全切缘宽度的共识或指南。保乳手术应该保证切缘无瘤，否则肿瘤的残留将使得一个根治性的手术人为转变成为姑息手术及活检手术；将随后的辅助治疗人为转变成为解救治疗。

Margin status after breast conserving surgery of breast cancer        ZHENG Xin-yu. Department of Breast Surgery, the First Affiliated Hospital, China Medical University, Shenyang 110001，China
Abstract    There is a general consensus among the surgeons that in breast conserving surgery (BCS) the margins of the specimen have to be tumor free and residual cancer following BCS increases the risk of local recurrence and mortality, but no universal agreement on the width of the tumor free margin duo to the different methods of margin assessment and BCS procedure. Basically, the specimen of BCS should have tumor free margins, otherwise the radical operation will be changed to palliative resection and excisional biopsy; and following adjuvant therapy will become salvage treatment, artificially.