胆囊癌是胆道系统最常见的恶性肿瘤, 令人遗憾的是，目前胆囊癌的诊断和治疗仍无突破性进展。胆囊癌相关基因有c-myc，Bcl-2，p53，p16 survivin。应重视胆囊癌基础研究, 注重各个科研机构的合作和协调，避免资源浪费，强调资源共享。同时需制定一套适合我国国情的胆囊癌诊疗指南。

Research status of gallbladder carcinoma sicken mechanism        ZOU Sheng-quan. Department of General Surgery, Tongji Hospital, Tongji Medical College Huazhong University of Science & Technology, Wuhan430030, China
Abstract    Gallbladder carcinoma is a common malignant cancer. But there is no significant breakthrough in the diagnosis and therapy. The genes related to gallbladder carcinoma are c-myc，Bcl-2，p53 and p16 survivin. It should emphasize the importance of basic research of gallbladder carcinoma and cooperation between different research institutions to achieve the resources sharing, avoid the waste of resources and propose to develop the suitable guideline of gallbladder carcinoma for China.