胃肠间质瘤（gastrointestinal stromal tumors，GIST）是胃肠道最常见的间质肿瘤，占全部软组织肉瘤的5%。回顾性研究发现10%～30%的GIST病人无明显症状，仅于外科手术中、放射线检查、内镜检查甚至是尸检时无意中发现。GIST同时合并胃肠癌的发病率尚不明确，且GIST多无明显症状，故过去10年间多以个案报告的形式见著于期刊。然而随着对GIST的认识和检查手段的进步，此类同时多源性肿瘤的发生率可能被低估了。

Diagnosis and management for synchronous multitumors of the gastrointestinal carcinoma and gastrointestinal stromal tumor        YE Ying-jiang, GAO Zhi-dong, WANG Shan. Department of Gastrointestinal Surgery, Peking University People’s Hospital, Beijing 100044, China
Corresponding author: WANG Shan, E-mail: shwang60@263.net.
Abstract    Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, accounting for 5% of all sarcoma in soft tissue. Retrospective studies showed 10%～30% of GISTs are completely asymptomatic at presentation, being found incidentally at surgery, radiographic imaging, endoscopy and even identified as chance findings at autopsy. Little is known about the actual incidence of incidental GIST with other gastrointestinal malignancy. The multitumors have been reported rarely. However, with the advances in understanding of GIST nature and inspection methods, the incidence rate may be underestimated.