肝内胆管结石病人要根据不同的病症进行合理的个体化治疗。首先，要根据病人的临床表现，是否存在急性胆管炎、败血症等并发症，而做相应的紧急处理。对合并有重症急性胆管炎者，旨在控制胆道感染、暂时通畅胆流、改善肝功能，待病情稳定后择期行根治性手术。肝内胆管结石病的治疗原则有三点：（1）尽量取净结石、清除病灶；（2）解除梗阻、矫正狭窄；（3）通畅引流、防治复发。

Diagnosis and treatment of primary hepatolithiasis Lau Wan-Yee, Lai Chun-Hung, Lau Hiu-Yan. The Chinese University of Hong Kong, Hong Kong, China Corresponding author: Lau Wan-Yee, E-mail: josephlau@cuhk.edu.hk Abstract The best definitive management of primary hepatolithiasis is to use a multidisciplinary approach. The basic principle of management of primary hepatolithiasis is to control infection during an acute attack of cholangitis, and then to eradicate all stones, strictures, and destroyed liver segments by elective definitive surgery when the disease is quiescent. The type of definitive procedures for patients who settled on conservative measures depends on the frequency and severity of each attack, presence of biliary strictures, and any existing co-morbid medical conditions of the patients.