输血感染严重威胁输血安全。虽然随着人们自愿无偿献血观念的增强、新的更高效的致病原检测和灭活技术的推广以及临床正规、合理用血的开展，输血安全性在不断提高。但是一些已发现并证实的血液传播病原体还未能完全检出和清除；而一些新的经血传播的病原体又不断被发现，这无疑都对输血安全造成威胁。

Blood transfusion infection and blood transfusion safety WANG Xing-hua, FANG Guo-en, QI Zhong-tian. The Second Military Medical University, Shanghai 200433, China Corresponding autuor: QI Zhong-tian,E-mail:tianhua72@sina.com Abstract Transfusion-transmitted infections have been a major threat to the safety of transfusion, although remarkable advances have been made in the prevention of the major transfusion-transmitted diseases due to improvement in donor screening, testing and viral inactivation of blood products, and rational use of blood in clinical works. At the same time, some established blood-borne pathogens can not yet be detected and cleared thoroughly, besides, novel agents have now appeared, and are still emerging. This presents continuous menaces to the safety of blood transfusion. The authors have highlighted the different transfusion-transmitted infections and the update on the screening technologies, and have focused on the precautionary strategies that can be implemented for improvements in blood safety.