目的:探讨乳腺癌保乳手术后发生延迟性蜂窝织炎（DBC）的高危因素。方法:回顾性分析2001年1月至2006年12月北京大学第一医院乳腺疾病中心诊治的152例保乳手术病人，根据诊断标准对14例确诊保乳术后DBC病人的临床资料进行回顾性分析，采用Pearson相关性检验分析影响DBC发生的因素。结果:DBC的发生率为9.2%（14/152），平均发生于术后6.2个月。肿瘤T分期、原发肿瘤部位、腋窝淋巴结清扫数目>15个、术后乳腺血肿/血清肿形成与DBC的发生有相关性。而年龄、糖尿病、新辅助化疗、腋窝淋巴结转移与DBC的发生无关。结论:手术及放疗造成乳腺淋巴通路回流障碍可能是保乳术后发生DBC的重要因素，对这一并发症的认识和治疗水平的提高，可以改善乳腺癌保乳术后病人的生活质量。

Objective:To analyze the risk factors of delayed breast cellulitis (DBC) after breast conserving surgery in breast cancer. Methods:The clinical data of 152 patients received breast conserving surgery during January 2001 to December 2006 in Breast Disease Center of Peking University First Hospital were analyzed retrospectively.All the patients were identified by the accepted criteria: diffuse breast erythema,edema,tenderness,and warmth occurring >3 months after definitive surgery and >3 weeks after radiotherapy.Forteen patients were diagnosed DBC. Results:The incidence of DBC in the group was 9.2% (14/152). The median time to onset of DBC was 6.2 months after breast conserving surgery.Primary tumor T stage, upper outer quadrant tumor,>15 axillary lymph nodes removed and the breast hematoma/seroma after surgery,were significantly associated with DBC.Age,diabetes,neoadjuvant chemotherapy, positive axillary lymph nodes metastasis were not the factors associated with DBC. Conclusion:Lymphatic drainage damaged by surgery procedures and radiotherapy maybe the most important factors contributed to the onset of DBC.