目的:研究脱细胞真皮基质材料治疗肛瘘的临床效果。方法:将北京朝阳医院2007年1~8月门诊收治的46例肛瘘随机分为2组，治疗组（23例）采用脱细胞真皮基质材料填塞进行治疗，对照组（23例）采用肛瘘切除手术治疗。结果:治疗组在疼痛、伤口愈合时间、肛门畸形等方面明显优于对照组(P<0.05)，肛瘘均治愈。结论:应用脱细胞真皮基质材料治疗肛瘘，具有微创、痛苦轻、疗程短和不损害肛门功能及外形的优势。

Objective:Observe the effects of the anal fistula treatment with acellular dermal matrix. Methods:46 case severy kind of anal fistula patients were randomly divided into 2 groups:treatment group (23 cases) Were treated with acellular extracellular matrix.Control group (23 cases) were treated with operations of anal fistula amputate. Results:The ache、healing time and anal deformation of treatment group were obviously superior to that of control group.The healing rate of anal fistula for treatment group is 100%. Conclusion:This method has advantages of mininal invasion,light pain,shorter course,protecting anal function and formation.