Abstract: Peri-implantitis is one of the main causes of late-stage implant failure. Currently，the treatments mainly consist of non-surgical and surgical sequential treatments. In 2018，American Academy of Periodontology（AAP）and European Federation of Periodontology（EFP）jointly issued a consensus report on the new classification of periodontal and peri-implant diseases，which clarified the classification and diagnostic criteria of peri-implant diseases. In 2023，EFP issued S3 clinical guidelines for the prevention and treatment of peri-implant diseases，and formulated a comprehensive treatment plan for peri-implantitis. According to a 5-year follow-up of a case of peri-implantitis with regenerative treatment，the clinical practice and insights of peri-implantitis was described from the aspects of diagnosis，etiology，risk factors，non-surgical treatment，surgical treatment（soft and hard tissue surgery）and supportive care based on the 2023 clinical guidelines and 2018 new classification. 

Key words: peri-implantitis, guidelines for the prevention and treatment, regenerative therapy

摘要： 种植体周炎是远期种植失败主要原因之一，目前治疗方案以非手术和手术序列治疗为主。2018年美国牙周病学会（AAP）和欧洲牙周病学联合会（EFP）共同发布了牙周病与种植体周病新分类相关共识报告，明确了种植体周围疾病分类及诊断标准。2023年EFP发布种植体周围疾病诊疗S3级临床防治指南，制定了种植体周炎的综合治疗方案。文章通过对1例种植体周炎采取再生治疗5年随访取得良好疗效病例进行总结，基于2018年新分类和2023年临床防治指南，从诊断、病因及危险因素、非手术治疗、手术治疗（软硬组织手术）和支持照护等方面阐述种植体周炎诊疗的临床应用实践及考量。

关键词: 种植体周炎, 防治指南, 再生治疗