关键词: 放射性口腔黏膜炎, 风险评估, 临床分级, 临床质量改进

Abstract: Radiation-induced oral mucositis（RIOM）is a common toxic reaction that may limit continuous treatment in head-and-neck radiotherapy and chemoradiotherapy. It typically presents with oral mucosal erythema，erosions or ulcers，and severe pain，often accompanied by malnutrition and infection. Based on current national and international guidelines and the Chinese group standards，this paper puts forward an integrated，full-cycle management model，including：systematic oral evaluation，risk stratification，and health education before radiotherapy；standardized oral hygiene management supported by appropriate local or systemic prophylactic measures through the course of treatment；severity-based therapeutic strategies that combine analgesia，anti-infection，nutritional support，and pro-healing interventions during treatment，with radiotherapy plan optimized if necessary；regular follow-up combined with patient-reported outcome measures（PROMs）and quality improvement（QI）indicators to form a closed management loop. This model is designed to reduce the incidence of severe RIOM and treatment interruptions，accelerate healing，and improve patients′quality of life.

Key words: radiation-induced oral mucositis, risk assessment, clinical grading, clinical quality improvement