关键词: 牙周加速成骨正畸术, 浓缩生长因子, 牙周表型, 数字化技术

Abstract: Objective    To study the effect of concentrated growth factor（CGF）combined with periodontally accelerated osteogenic orthodontics（PAOO）on periodontal soft and hard tissue reconstruction in the lower anterior teeth of patients of thin gingival phenotype. Methods    Twenty patients of thin gingival phenotype（118 lower anterior teeth）were selected，who attended the orthodontic department of Hefei Stomatological Hospital and were referred to the periodontal department for PAOO in the lower anterior region from January 2023 to April 2024， and they were divided into a study group（10 cases，58 lower anterior teeth）and a control group（10 cases，60 lower anterior teeth）by using a randomised numerical table method. The study group was implanted with CGF gel and Bio-Oss bone powder at a mass ratio of 1∶1，covered with a CGF membrane+collagen membrane during the PAOO procedure，and the control group was implanted with Bio-Oss bone powder only，covered with a collagen membrane during the procedure. Changes in probing depth（PD），bleeding index（BI），gingival recession depth（RD），keratinised gingival width，gingival thickness，and labial mid-root bone thickness were compared between the 2 groups preoperatively and 6 months postoperatively. Results    Preoperatively and at 6 months postoperatively，there was no statistically significant difference in PD，BI or RD between the study group and the control group（all P > 0.05）. At 6 months postoperatively，the bone thickness in the labial side of the mid-root increased by（1.14 ± 0.24）mm and（1.03 ± 0.26）mm，and the gingival thickness increased by（0.35 ± 0.15）mm and（0.17 ± 0.15）mm in the study group and the control group，respectively，compared with the preoperative period；the difference in the increase in the thickness of the bone in the labial side of the mid-root and the gingival thickness in the 2 groups was statistically significant（t values being 2.340，6.388，both P < 0.05）. The keratinised gingival width also increased in both groups compared to the preoperative period，but the difference was not statistically significant when comparing the amount of increase（P > 0.05）. At 6 months postoperatively，there were 38 lower anterior teeth with gingival thickness > 1 mm（65.5%）in the study group and 17 lower anterior teeth with gingival thickness > 1 mm（28.3%）in the control group，and the difference between the two was statistically significant（χ2 = 16.386，P < 0.001）. Conclusion    CGF applied to the PAOO procedure improves the periodontal phenotype in patients of thin gingival phenotype and enhances the postoperative periodontal soft and hard tissue reconstruction of the lower anterior teeth.

Key words: periodontally accelerated osteogenic orthodontics, concentrated growth factor, periodontal phenotype, digital technology