中国实用口腔科杂志 ›› 2024, Vol. 17 ›› Issue (1): 118-123.DOI: 10.19538/j.kq.2024.01.020

• 综述 • 上一篇    下一篇

聚维酮碘辅助治疗牙周炎研究进展

刘恩言1,丁    一1,2,刘程程1,2,段丁瑜1,2   

  1. 1. 口腔疾病防治全国重点实验室 国家口腔医学中心 国家口腔疾病临床医学研究中心,四川  成都  610041;2. 四川大学华西口腔医院牙周病科,四川  成都  610041
  • 出版日期:2024-01-30 发布日期:2024-02-29
  • 基金资助:
    四川省自然科学基金面上项目(2022NSFSC0773)

  • Online:2024-01-30 Published:2024-02-29

摘要: 牙周炎是一种以牙菌斑生物膜为始动因子的慢性炎症性疾病,机械清除牙菌斑是目前治疗牙周炎的主要手段。然而,在某些牙周组织病变中,器械不易到达感染部位,且口腔内其他部位的微生物可再定植于牙周袋。此外,当患者处于急性炎症期或牙周手术后暂时不能行口腔卫生措施等情况时,配合局部抗菌药物可取得更好疗效。聚维酮碘具有广泛的抗菌谱,可快速杀灭牙周病原体,促进创口愈合,毒性低且不会导致耐药,是一种有潜力的牙周局部用药。文章就近年来聚维酮碘在辅助治疗牙周炎方面的研究和现状做一综述,为牙周炎的药物治疗提供更多参考信息。

关键词: 聚维酮碘, 牙周炎, 牙菌斑控制, 牙周基础治疗

Abstract: Periodontitis is a chronic inflammatory disease with dental plaque as the initial factor. To date,the main method in the treatment of periodontitis is mechanical plaque removal. However,in periodontal diseases there are infected sites that are not easily accessible to instruments,and microorganisms from other parts of the oral cavity can re-colonized the periodontal pocket. In addition,if patients have acute infections or are temporarily unable to perform oral hygiene measures after periodontal surgery,the application of local antibacterial drugs can achieve better efficacy. Povidone iodine(PVP-I),with its extensive antibacterial spectrum,can quickly kill periodontal pathogens and promote wound healing. It is a potential periodontal auxiliary drug with low toxicity and won′t cause bacterial drug resistance. This review summarized the researches and current status of povidone iodine in the adjuvant treatment of periodontitis in recent years,aming to provide more reference information for the drug treatment of periodontitis.

Key words: povidone iodine, periodontitis, plaque control, initial periodontal treatment