关键词: 重度牙周炎, 牙周基础治疗, 牙周-正畸联合治疗, 牙周支持治疗

Abstract: The difficulty and complexity in management of severe periodontitis have greatly increased due to serious destruction of periodontal supportive tissue and difficult control of inflammation. Multidisciplinary professional means and close cooperation between each other are particularly necessary in the treatment design and implementation for complicated periodontitis cases with malocclusion. This article illustrated a case of generalized stage Ⅳ grade C periodontitis which had been followed-up for 21 years. Through initial periodontal therapy，orthodontic therapy and periodontal maintenance，the patient obtained health，function and aesthetics as well as a long-term stable effect，which provides ideas and clinical experience for combined periodontal and orthodontic treatment of such cases of severe periodontitis with malocclusion.

Key words: severe periodontitis, initial periodontal therapy, combined periodontal and orthodontic treatment, supportive periodontal therapy