关键词: 重度牙周炎, 多学科治疗, 牙颌面畸形, 膜龈手术

Abstract: The patients with severe periodontitis often have dentition defect and dentofacial deformities，and their normal oral function and appearance are seriously affected. With the demands of patients for restoration of oral health，function and aesthetics increasing，the treatment goals for severe periodontitis patients with dentofacial deformities should include establishing good occlusal contact，achieving sustained and stable periodontal health and taking into account masticatory function and restoration of dentofacial aesthetics. It usually requires complex multidisciplinary treatment，which is critical and difficult for clinical diagnosis and treatment. This article displays the multidisciplinary treatment procedures，including initial periodontal therapy，mucogingival surgery，orthodontic and orthognathic combined treatment，and a long-term follow-up of a patient with generalized stage Ⅲ grade C periodontitis and skeletal class Ⅲ malocclusion，which finally achieve the goals of restoring health，reconstructing function and esthetic improvement. It is expected to provide some experiences for the multidisciplinary treatment of clinical complex cases. 

Key words: severe periodontitis, multidisciplinary treatment, dentofacial deformity, mucogingival surgery