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02 June 2016, Volume 32 Issue 6 Previous Issue    Next Issue

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Prevention of HIV transmission from mother to child. SUN Jian-jun，LU Hong-zhou. 2016, 32(6): 511-514.  DOI: 10.7504/fk2016050106 Abstract ( )   Abstract: With the enlargement of HIV epidemic and the progress of antiretroviral therapy，more and more young people get infected and the quality of life become better and better with the antiretroviral treatment.Many of the infected women wish to get pregnancy，and thus clinical staff needs to learn how to help them to get a healthy baby.Factually，there is a gap between advanced countries and China in the rate of successful MTCT prevention.There is no doubt that diagnosing HIV and initiating antiretroviral therapy earlier will do good to the outcome of pregnancy.Additionally，appropriate mode of delivery and regimen of neonatal prophylaxis should be determined according to the results of antenatal monitoring.

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Early screening and treatment for syphilis in pregnancy and its effect on pregnancy outcome. LIU Ping，FAN Shang-rong. 2016, 32(6): 514-517.  DOI: 10.7504/fk2016050107 Abstract ( )   Abstract: Syphilis in pregnancy not only harms mothers' health，but also leads to fetal growth restriction，non-immune hydrops fetalis，miscarriage，premature birth，stillbirth and congenital syphilis and other adverse pregnancy outcomes.The early screening，proper penicillin therapy and follow-up for syphilis in pregnancy and their infants are important to prevent adverse outcome.Over diagnosis and therapy of congenital syphilis also should be avoided.

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Diagnosis and standard treatment of pregnancy with gonorrhea. LI Li，LI Yin-feng. 2016, 32(6): 517-519.  DOI: 10.7504/fk2016050108 Abstract ( )   Abstract: Gonorrhea is a bacterial sexually transmitted disease caused by Neisseria gonorrhoeae.Pregnancy with gonococcus infection is not uncommon，and gonorrhea may cause adverse pregnancy outcome and neonatal harm. When it is serious the Neisseria gonorrhoeae may travel through the blood cause disseminated gonococcal infection，which should be paid attention to by obstetricians.Early diagnosis，clinical typing，the choice of the most sensitive drug and enough，regular and correct treatment is very important.

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Screening, diagnosis and management of group B streptococcus infection in perinatal pregnancy. YING Hao,MENG Zhen-ni. 2016, 32(6): 520-522.  DOI: 10.7504/fk2016050109 Abstract ( )   Abstract: Group B Streptococcus is a gram-positive coccus which is very important in pregnancy.The infection with group B Streptococcus in pregnant women can lead to the adverse effects on pregnancy outcome.Maternal and neonatal clinical outcomes have been improved by screening and treatment of GBS in developed countries.There is no unified GBS screening and treatment guidelines in our country.This article will review the status and controversy of GBS screening in China.

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Perinatal genitourinary infections and preterm birth. DU Juan，HUANG Zhen-jiao. 2016, 32(6): 522-525.  DOI: 10.7504/fk2016050110 Abstract ( )   Abstract: Genitourinary infections are one of the most important factors to induce preterm birth.The risk of preterm delivery has been increased by any kind of genitourinary tract infection.The mechanisms of preterm birth have not been fully elucidated yet.Some evidences indicate that imbalance of immune homeostasis may play an important role， and prostaglandin may also increase the risk of preterm birth.What's more， the gene polymorphism can make something even clear.There are many scholars who have different opinions on the importances of early screening of perinatal genitourinary infections.However， early screening of urinary and reproductive tract infections to prevent premature is necessary for people at a high risk for preterm birth.

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Near-and long-term influence of perinatal infection on the children’s central nervous system. FU Jian-hua,ZHANG Dan. 2016, 32(6): 525-528.  DOI: 10.7504/fk2016050111 Abstract ( )   Abstract: The pathogenic microorganisms of perinatal infection include bacteria，viruses，protozoa，etc.It increases the risk of perinatal brain injury which is even more serious than hypoxia ischemic injury ,when fatal immature brain is exposed to intrauterine infection/inflammation.The bad neurodevelopmental outcomes not only include cognitive disorders，epilepsy，cerebral palsy，but also increase the risk of children suffuring autism and schizophrenia.Here we have a overview of perinatal infection and emphase on the near-and long- term influence of perinatal infection on the children’s central nervous system.

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Chorioamnionitis and fetal and neonatal diseases. HAN Tong-yan，YANG Zi，PIAO Mei-hua. 2016, 32(6): 529-534.  DOI: 10.7504/fk2016050112 Abstract ( )   Abstract: Chorioamnionitis as a major risk factor contributes to prematurity-associated mortality and morbidity.Fetal inflammatory response syndrome (FIRS) should not be ignored.Prompt diagnosis can help avert the significant short-term (endometritis，neonatal sepsis and perinatal infections) and long-term consequences (infant’s systemic and neurologic sequelae) .This article aims to summarize the short-term outcomes and long-term sequaelas of chorioamnionitis，and calls for future studies which aim to better understand the mechanism of disease and to develop better detection and intervention methods to prevent the significant associated morbidity.