Abstract: Aplastic anemia is a serious and rare complication of pregnancy which may lead to maternal anaemia，infection，bleeding，fetal growth restriction and intrauterine death during pregnancy and childbirth.A series of measures are expected to improve the outcomes of the mothers and newborn babies and minimize the burden of disease and complications， including comprehensive and detailed assessment of the condition before pregnancy，choosing the best time for pregnancy，multidisciplinary management and treatment after pregnancy，medical support or medication when necessary，peripartum decision of childbirth timing and delivery mode according to the condition of the complications，active prevention of postpartum bleeding and infection and follow-up examination and treatment by hematology department after delivery.

Key words: aplastic anemia, pregnancy, perinatal management

摘要： 再生障碍性贫血是一种严重而少见的妊娠合并症，在妊娠和分娩过程中可引起孕产妇贫血、感染、出血及胎儿生长受限、胎死宫内等风险。孕前对病情全面详尽的评估，掌握妊娠的最佳时机；妊娠后多学科联合管理和治疗，必要的支持或药物治疗；围分娩期根据病情考虑计划分娩时机和分娩方式，积极预防产后出血和感染；分娩后血液内科严格随诊等措施的实施有望改善产妇及新生儿的结局，最大限度地减轻疾病负担和并发症。

关键词: 再生障碍性贫血, 妊娠, 围产期管理