Abstract: Oxytocin plays an irreplaceable role in reducing cesarean delivery rates and shortening labor processing，which is widely used in clinic. However，the unregulated clinical application of oxytocin is associated with increased risks of adverse pregnancy-related complications and outcomes for both mothers and infants. To date，there has been no agreement about the dosage，treatment timing，frequency of application. Therefore，it will help clinicians to ensure medication safety that finding greatest medication use，treatment timing and dosage，specifying management，enhancing surveillance.

摘要： 缩宫素是目前临床上应用最广泛的催产、引产药物，在有效缩短分娩时间及降低剖宫产率方面发挥着不可替代的作用。但缩宫素的不规范使用也会增加母儿并发症的发生率。临床实践中对于缩宫素的使用剂量、方法、时机以及活跃期是否停用等方面尚未达成一致。因此，寻找缩宫素的最佳用药剂量、把握用药时机、合理规范使用的同时避免不规范使用带来的严重不良结局，是保障用药安全及成功经阴道分娩的关键。