Abstract: Considering the causes and potential risks of membrane rupture，induction of near-term and full-term premature rupture of membranes is of more positive significance than expected treatment. All PROM patients without contraindication to vaginal delivery may be considered for induction of labor within 2 to 12 hours or 24 hours after rupture of the membrane. Oxytocin，misoprostol，denoprostol，and mechanical methods can be used for induction of labor in patients with PROM. However，attention should be paid to the exclusion of infection，pelvic imbalance and other unsuitable conditions for vaginal delivery before induction，and more appropriate methods should be selected according to the patient's birth times and cervical Bishop score. In the process of induction of labor，we should also pay attention to the dynamic assessment of maternal and fetal conditions and progress of labor，and conduct individualized management.

摘要： 综合考虑破膜原因、潜在风险等，近足月及足月胎膜早破（premature rupture of membrane，PROM）的引产较期待治疗更具积极意义。所有无阴道分娩禁忌证的PROM产妇均可考虑在破膜后2～12 h或24 h内进行引产。缩宫素、米索前列醇、地诺前列酮及机械性方法等均可用于PROM患者的引产，但在引产前应注意排除感染、头盆不称等不宜阴道分娩的情况，并根据患者产次、子宫颈Bishop评分选择更适宜的引产方法。引产过程中也应注意动态评估母儿状况和产程进展，进行个体化管理。