Abstract:

Polycystic ovary syndrome（PCOS）is a common disease with endocrinal disorder in fertile women，which is usually characterized by anovulation，hyperandrogenism and insulin resistance.Endocrinal disorders make patients with PCOS be prone to develop obesity.Obesity interacts with PCOS，and they both increase the risk of infertility，pregnancy complications and long-term complications.Thus，the patient needs to undergo health status assessment，lifestyle modification，medications or even surgery before assisted reproduction in order to improve the outcomes of assisted reproduction and reduce the risk of pregnancy complications and long-term complications.

Key words: polycystic ovary syndrome, obesity, management before assisted reproduction, pregnancy outcomes

摘要：

多囊卵巢综合征（PCOS）是育龄期女性常见的内分泌紊乱综合征，通常表现为持续性无排卵、高雄激素血症、胰岛素抵抗等。内分泌紊乱状态使PCOS患者容易伴肥胖，肥胖又可与PCOS内分泌紊乱发生相互作用，共同增加患者不孕不育的风险，影响助孕结局，并增加妊娠合并症及远期并发症的风险。故对此类患者行助孕前需要详细评估身心健康状态，调整生活方式，必要时辅以药物甚至手术，以达到改善助孕结局、降低妊娠合并症及远期并发症风险的目的。

关键词: 多囊卵巢综合征, 肥胖, 助孕前处理, 妊娠结局