Abstract:

Primary female genital system lymphoma（PFGSL） is one kind of extranodal lymphoma.PFGSLs include ovarian lymphomas，cervical lymphomas and vulvar lymphomas.Most of PFGSLs are type B non- Hodgkin’s lymphoma.The diagnosis is based on pathology and immunohistochemistry.The treatment strategies include CHOP-based chemotherapy，targeted therapy，radiotherapy and surgery.The purpose of surgery is to clarify the pathology.Rituximab has been demonstrated to improve the prognosis of lymphoma.The prognosis of PFGSL is good.

Key words: primary female genital system lymphoma（PFGSL）, pathology, chemotherapy, targeted therapy

摘要：

女性生殖器官恶性淋巴瘤是结外淋巴瘤的一部分，可发生于卵巢、宫颈、外阴等部位。病理类型多为B细胞型非霍奇金淋巴瘤，确诊依赖病灶及淋巴结的病理和免疫组化检查。治疗原则以化疗及靶向治疗为主，辅以放疗和手术治疗。环磷酰胺+多柔比星+长春新碱+泼尼松（CHOP）为首选化疗方案，手术以获取足够病理确诊的组织为目的，不主张过大手术范围。以美罗华为代表的靶向药物在淋巴瘤中的疗效已被认可。预后相对良好。

关键词: 女性生殖器官恶性淋巴瘤, 病理, 化疗, 靶向治疗