The initial treatments for epithelial ovarian cancer include cytoreductive surgery，platinum-based chemotherapy and maintenance therapy. In this article，we present the evolution and standardized application of first-line chemotherapy for newly diagnosed epithelial ovarian cancer. The regimen of paclitaxel followed by carboplatin every three weeks is still the preferred regimen for newly diagnosed epithelial ovarian cancer and its outstanding status has never been replaced. In this article，we also review the indications for bevacizumab and other recommended regimens for newly diagnosed epithelial ovarian cancer. At the end，we point out the problems of non-standardized chemotherapy in clinical practice and stress the importance of standard chemotherapy in order to help increase the survival rate of patients with advanced epithelial ovarian cancer.