Analysis of the indications for terminating pregnancy in severe preeclampsia without complications.

CHEN Yang, YANG Zi, SONG Ying,WANG Jia-lüe,SHEN Jie.

Chinese Journal of Practical Gynecology and Obstetrics ›› 2014, Vol. 30 ›› Issue (9) : 717-721.

Chinese Journal of Practical Gynecology and Obstetrics ›› 2014, Vol. 30 ›› Issue (9) : 717-721. DOI: 10.7504/fk2014080119

Analysis of the indications for terminating pregnancy in severe preeclampsia without complications.

  • CHEN Yang, YANG Zi, SONG Ying,WANG Jia-lüe,SHEN Jie.
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Abstract

Abstract: Objective To analyze the current status and affecting factors of terminating pregnancy in severe preeclampsia without complications at admission . Methods Clinical observational data of 330 cases of severe preeclampsia (sPE) without serious complications at admission in Peking University Third Hospital, a tertiary teaching hospital, from Jan.2009 to Dec.2012 were analyzed. Cases were divided into groups according to the gestation-weeks (GW) at termination. Results A total of 330 cases of sPE without serious complications at admission accounted for about 83.3% of all cases of sPE diagnosed at discharge. There were 3/5 of cases with GW (<26-GW) considerations terminated pregnancy. Social factor was the independent influencing factor in the 26~<28 GW group. Isolated massive proteinuria (>10g/24h)and serious complications occurrence were the main termination indications in the 28~<30 GW group. The independent factors in sequence were social factor, maternal factors, fetal factors and placenta factors(P<0.05). In the 30~<32GW group, the main termination indication was serious complications occurrence. The independent factors in sequence were maternal factors, massive proteinuria, placenta factors and fetal factors (P<0.05). In the 32~<34GW group, the main termination indications were massive proteinuria, uncontrolled hypertension and abnormal fetal monitoring. The independent factors in sequence were maternal factors , fetal factors and placenta factors. In the 34~<36GW group, GW(≥34-GW) consideration accounted for about 44.3%. The independent factors in sequence were GWconsideration, uncontrolled hypertension, abnormal S/D ratio and abnormal fetal monitoring (P<0.05). In the ≥36 GW group, about 68.3% cases terminated pregnancy under consideration of ≥36-GW. Conclusions This research shows that although there are various indicating factors affecting the termination of sPE pregnancy without serious complications,the fact of pure consideration of massive proteinuria and GW also exist. Whether it is appropriate to take the quantity of urine protein or GW alone as the indication of terminating pregnancy in isolated sPE will need further research and extensive clinical evidence.

Key words

severe preeclampsia / pregnancy termination;complications

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CHEN Yang, YANG Zi, SONG Ying,WANG Jia-lüe,SHEN Jie.. Analysis of the indications for terminating pregnancy in severe preeclampsia without complications.[J]. Chinese Journal of Practical Gynecology and Obstetrics. 2014, 30(9): 717-721 https://doi.org/10.7504/fk2014080119

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(2014-04-09收稿    2014-06-28修回)

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