Abstract: The commonly used prenatal diagnosis methods for placenta accreta spectrum disorders are mainly clinical risk factors combined with imaging examination，but its accuracy is somewhat subjective. With the deeper study on the pathogenesis of the diseases，the possibility of serological markers as an adjuvant examination is gradually recognized. This review intends to summarize the current researches on potential biomarkers for placenta accreta spectrum disorders，and explore their significance in prenatal diagnosis and their application values.

Key words: placenta accreta spectrum disorders, prenatal diagnosis, molecular biomarkers, angiogenesis

摘要： 胎盘植入性疾病目前常用的产前诊断方法主要是临床高危因素结合影像学检查，然而其准确度存在一定的主观性。随着对胎盘植入性疾病发病机制的深入研究，血清学分子标志物作为辅助诊断的可能性被逐渐认可，文章拟总结目前胎盘植入性疾病的潜在分子标志物研究进展，探讨其在胎盘植入性疾病产前诊断方面的意义和应用价值。

关键词: 胎盘植入性疾病, 产前诊断, 分子标志物, 血管生成