Acta Metallurgica Sinica

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Prevention of chemotherapy-induced ovarian damage in patients with gynecological malignant tumors.

  

  1. International Peace Maternity & Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China
  • Online:2019-06-02 Published:2019-06-03

妇科恶性肿瘤化疗患者卵巢功能保护

  

  1. 上海交通大学医学院附属国际和平妇幼保健院,上海200030
  • 通讯作者: 王玉东
  • 基金资助:

    上海交通大学医工交叉重点项目(YG2015ZD10);上海市卫生局“新百人计划”(优秀学科带头人)(XBR2013097)

Abstract:

Improvement in diagnosis has made it possible to have the early detection of gynecologic malignancies.Among premenopausal women,the loss of future fertility or ovarian function is considered among the most dreadful long-term side effects of treatments.Therefore,the preservation of fertility and ovarian function during chemotherapy treatment is of great important.This article will summarize the effect of chemotherapy on ovarian function and protective measures for chemotherapy-induced ovarian damage.

Key words: gynecologic malignant tumor, chemotherapy, ovarian function

摘要:

得益于肿瘤普查及诊断方法的进展,更多的妇科恶性肿瘤可在早期被发现。对于年轻患者,如何保留其卵巢功能及减轻后续的化疗对卵巢功能的损害,从而改善患者生存质量,提高生育能力显得尤为重要。文章针对妇科恶性肿瘤治疗过程中卵巢功能的保护,特别是化疗对卵巢的影响及其保护措施进行阐述。

关键词: 妇科恶性肿瘤, 化学治疗, 卵巢功能

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