Abstract:

Carcinosarcoma of the female genital tract is a rare but highly aggressive，easily recurrent malignancy with poor prognosis. Pathologically，carcinosarcoma is a biphasic neoplasm composed of a mixture of malignant epithelial and mesenchymal components. Studies have indicated that most carcinosarcomas are essentially high-grade  carcinomas with sarcomatous differentiation，which derive from a monoclonal neoplasm.A comprehensive approach to management is recommended with complete surgery，followed by multimodal therapy with combinations of external beam irradiation and/or systematic chemotherapy in patients with both early and advanced stage disease.

Key words: carcinosarcoma of the female genital tract, chemotherapy, radiotherapy, prognosis

摘要：

女性生殖道癌肉瘤是一类很少见、 侵袭性强、 易于复发转移、预后差的肿瘤。该类肿瘤包含癌和肉瘤两种恶性组织成分，目前的研究对此类肿瘤的起源更倾向于转化学说，即认为该类癌瘤为单克隆起源，其中肉瘤成分由癌细胞化生为肉瘤样成分。在治疗上，对癌肉瘤首选手术治疗，术后通常需采用辅助化疗和放疗等综合治疗。

关键词: 女性生殖道癌肉瘤, 化疗, 放疗, 预后