胎盘部位滋养细胞肿瘤是一种较少见的妊娠滋养细胞肿瘤，其最常见的临床表现为停经和阴道流血，确诊必须以组织病理学诊断为依据，免疫组化检查在其诊断与鉴别诊断中具有重要意义。其对化疗的敏感性不如其他类型滋养细胞肿瘤，手术是首选的治疗方法，对有不良预后因素的患者还应多药联合化疗进行综合治疗。对于年轻、有生育要求、且子宫病灶局限的病例可以考虑采用保留生育功能治疗。

Placental site trophoblastic tumor is a rare form of gestational trophoblastic disease.The most common clinical manifestations are amenorrhea and abnormal vaginal bleeding. The diagnosis must be based on pathological evidence.Immunohistochemistry plays an important role in the diagnosis and differential diagnosis of PSTT.PSTT is less chemosensitive than other forms of gestational trophoblastic neoplasm，thus operation is the primary treatment in most cases.Multiple agent chemotherapy combined with operation are recommended in patients with poor prognostic factors.Fertility-preserving treatment can be considered in highly-selected cases.