中国实用妇科与产科杂志

中国实用妇科与产科杂志

• 专题笔谈 • 上一篇    下一篇

宫颈上皮内瘤变复发问题

冯定庆，凌斌   

  1. 作者单位：中日友好医院妇产科，北京 100029
  • 出版日期:2016-11-02 发布日期:2016-11-09
  • 通讯作者: 凌斌

Problems related to the recurrence of cervical intraepithelial neoplasia.

FENG Ding-qing，LING Bin.   

  1. Department of Obstetrics and Gynecology，China-Japan Friendship Hospital，Beijing 100029，China.
  • Online:2016-11-02 Published:2016-11-09

摘要：

高级别宫颈上皮内瘤变（cervical intraepithelial neoplasia，CIN）采用物理治疗或手术切除后，仍然存在复发的风险。CIN术后复发主要与手术方式、手术切缘状况、累及腺体、人乳头瘤病毒（HPV）持续感染以及局部免疫状态有关，年龄可作为一个术前预测指标。术后严密随访，及早确诊病灶残留或复发，采用扩大切除范围或行全子宫切除，避免漏诊和过度治疗。

关键词: 宫颈上皮内瘤变, 复发, 危险因素

Abstract:

Abstract： The recurrence of high-grade cervical intraepithelial neoplasia （CIN） is a significant problem after treatment with physiotherapy，cold knife conization （CKC），or loop electrosurgical excision procedure （LEEP）.The risk factors for recurrence of posttreatment CIN include incomplete resection，involved margins and glands，persistence of HPV，and immunodeficiency of cervix.Higher age at resection may be a preoperative indicator for recurrence.Close follow-up，timely diagnosis of residual lesions，expanded range of resection or hysterectomy，to some extent，well prevent the recurrence of CIN.Meanwhile，missed diagnosis and over-treatment must be avoided as much as possible.

Key words: cervical intraepithelial neoplasia, recurrence, risk factors

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