中国实用妇科与产科杂志

• 专题笔谈 • 上一篇    下一篇

复发性耐药性妊娠滋养细胞肿瘤的诊治

吕卫国   

  1. 作者单位:浙江大学医学院附属妇产科医院,浙江 杭州 310006
  • 出版日期:2015-03-02 发布日期:2015-04-01

Diagnosis and management of or recurrent resistant gestational trophoblastic neoplasia.

LÜ Wei-guo.   

  1. Women’s Hospital School of Medicine Zhejiang University,Hangzhou 310006,China
  • Online:2015-03-02 Published:2015-04-01

摘要:

尽管妊娠滋养细胞肿瘤对化疗高度敏感,但仍有10%患者化疗时耐药,或治疗后复发。耐药和复发后患者的治疗原则为化疗为主、辅以手术等的综合治疗。尽管补救化疗方案较多,但迄今尚无一个明确的高效、低毒的补救化疗方案。

关键词: 妊娠滋养细胞肿瘤, 化学治疗, 耐药, 复发

Abstract:

Abstract:Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 10% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.

Key words: gestational trophoblastic neoplasia, chemotherapy, resistant;recurrent

中图分类号: