Abstract: Pediatric cyclic vomiting syndrome（CVS）is a clinically common disorder of gut–brain interaction，whose pathogenesis has not been fully elucidated. Characterized by recurrent episodes，this condition is associated with high rates of emergency visits and hospital admissions for intravenous fluid therapy.It not only seriously impairs children’s growth，development and physical and mental health，but also places a heavy economic burden on affected families and society. Therefore，early identification and standardized diagnosis and treatment of this disorder are crucial.The newly released Rome V Criteria（2026）clearly state that the management of pediatric CVS must adopt a stepwise and individualized comprehensive treatment regimen based on the severity of episodes，the degree of functional impairment and psychosocial impacts. All patients require fundamental interventions，including lifestyle modification，behavioral therapy and alternative therapies. Meanwhile，the disease should be stratified by disease severity，and targeted abortive interventions are administered during acute attacks，alongside long-term prophylactic treatment during interictal periods.

Key words: cyclic vomiting syndrome, disorder of gut-brain interaction, pediatrics, children, therapy

摘要： 儿童周期性呕吐综合征（CVS）是一种临床常见的肠- 脑互动异常，其发病机制尚未完全阐明。该病呈反复发作特点，急诊就诊及住院输液率居高不下，不仅严重影响患儿生长发育与身心健康，还给患儿家庭和社会带来沉重的经济负担。因此，对该病开展早期识别和规范化诊疗至关重要。2026 年最新发布的罗马Ⅴ标准明确指出，儿童CVS 的治疗需要结合发作严重程度、功能障碍程度及心理社会影响，采取阶梯式、个体化综合治疗方案。所有患者均需基础管理干预，包括生活方式调整、行为干预与替代疗法；同时根据病情严重程度分级，针对性给予急性发作期的终止性干预措施以及发作间期长期预防性治疗。

关键词: 周期性呕吐综合征, 肠- 脑互动异常, 儿童, 治疗