中国实用儿科杂志

中国实用儿科杂志 ›› 2024, Vol. 39 ›› Issue (8): 631-635.DOI: 10.19538/j.ek2024080615

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鼻呼出气一氧化氮检测在儿童原发性纤毛运动障碍中的诊断应用

  

  1. 重庆医科大学附属儿童医院肺功能室 国家儿童健康与疾病临床医学研究中心 儿童发育疾病研究教育部重点实验室 儿童代谢与炎症性疾病重庆市重点实验室，重庆  400014
  • 出版日期:2024-08-06 发布日期:2024-09-23
  • 通讯作者: 刘莎，电子信箱：lsls2628@126.com
  • 基金资助:
    重庆市科卫联合医学科研项目（2022MSXM043）

Diagnostic application of nasal nitric oxide detection in primary ciliary dyskinesia in children

  1. Department of Pulmonary Function Laboratory，Children′s Hospital of Chongqing Medical University；National Clinical Research Center for Child Health and Disorders；Ministry of Education Key Laboratory of Child Development and Disorders；Chongqing Key Laboratory of Rdiatric Metabolism and Inflammatory Diseases，Chongqing 400014，China
  • Online:2024-08-06 Published:2024-09-23

摘要： 原发性纤毛运动障碍是一组源于气道的遗传异质性疾病，临床表现多样，诊断方式复杂，目前尚无公认的诊断金标准。鼻部一氧化氮检测与其他检查方式相比，操作简单且无创，价格相对低廉，越来越多地应用于儿童原发性纤毛运动障碍的筛查。该文主要探讨鼻部一氧化氮检测在儿童原发性纤毛运动障碍中的诊断应用。

关键词: 原发性纤毛运动障碍, 鼻呼出气一氧化氮, 儿童, 诊断

Abstract: Primary ciliary dyskinesia is a group of genetic heterogeneous diseases originating from the airway. It has various clinical manifestations with complex diagnostic methods，and there is no recognized gold standard for diagnosis at present. Compared with other examination methods，the detection of nasal nitric oxide is simple and non-invasive，and the price is relatively low. It is used more and more in the screening of primary ciliary dyskinesia in children. This paper mainly discusses the application of nasal nitric oxide detection in the diagnosis of primary ciliary dyskinesia in children.

Key words: primary ciliary dyskinesia, nasal nitric oxide, child, diagnosis