中国实用儿科杂志

中国实用儿科杂志 ›› 2026, Vol. 41 ›› Issue (1): 16-19.DOI: 10.19538/j.ek2026010604

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新生儿缺氧缺血性脑病的诊治：机遇与挑战

  

  1. 1.复旦大学附属儿科医院新生儿科，上海  201102；2.广州医科大学附属妇女儿童医疗中心新生儿科，广东  广州  510623
  • 出版日期:2026-01-06 发布日期:2026-02-25
  • 通讯作者: 周文浩，电子信箱：zhouwenhao@fudan.edu.cn
  • 基金资助:
    科技部国家重点研发计划［2024YFC2707700］

Diagnosis and treatment of hypoxic-ischemic encephalopathy in neonates： opportunities and challenges

  1.  *Department of Neonatology，Children’s Hospital of Fudan University，Shanghai  201102，China
  • Online:2026-01-06 Published:2026-02-25

摘要： 新生儿缺氧缺血性脑病（HIE）是围生期缺氧缺血导致的多环节、多因素病理生理级联反应，可造成神经系统急性乃至永久性损害。国内HIE的规范化诊断与治疗策略仍面临困难与挑战，如何在强调“早识别、准预测、多联合、重随访”的核心原则基础上，进一步推动基于多模态评估的个体化神经保护策略，是临床实践未来重点发展的方向。

关键词:

Abstract: Hypoxic-Ischemic Encephalopathy（HIE） in newborns is a multi-stage，multi-factor pathophysiological cascade reaction caused by perinatal hypoxia-ischemia，which can lead to acute or even permanent damage to the nervous system. The standardized diagnosis and treatment strategies for HIE in China still face difficulties and challenges. How to further promote individualized neuroprotective strategies based on multimodal assessment，while emphasizing the core principles of “early recognition，accurate prediction，multiple combinations，and close follow-up，” is a key direction for future development in clinical practice.

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