中国实用儿科杂志

中国实用儿科杂志 ›› 2025, Vol. 40 ›› Issue (6): 492-496.DOI: 10.19538/j.ek2025060610

• 专题笔谈 • 上一篇    下一篇

儿童艰难梭菌感染的诊断与治疗

  

  1. 国家儿童医学中心  首都医科大学附属北京儿童医院消化科，北京  100045
  • 出版日期:2025-06-06 发布日期:2025-08-29
  • 通讯作者: 吴捷，电子信箱：wujie@bch.com.cn
  • 基金资助:
    北京市医院管理中心“ 登峰”人才培养计划（DFL20221003）；高层次公共卫生技术人才建设项目培养计划（学科带头人-02-04）

Diagnosis and treatment of Clostridium difficile infection in children

  1. Department of Gastroenterology，Beijing Children’s Hospital，Capital Medical University，National Center for Children’s Health，Beijing  100045，China
  • Online:2025-06-06 Published:2025-08-29

摘要： 艰难梭菌是儿童急性感染性腹泻的主要病原之一。随着抗生素的广泛使用，艰难梭菌感染的发病率及复发率明显增高。文章总结国内外相关研究及指南共识，从儿童艰难梭菌感染的流行病学、危险因素、临床特征及治疗防控措施等方面，阐述儿童艰难梭菌感染的诊断与治疗。

关键词: 艰难梭菌, 诊断, 粪菌移植, 儿科人群

Abstract: Clostridium difficile is one of the main pathogens causing acute infectious diarrhea in children. With the widespread use of antibiotics， the incidence and recurrence rate of C. difficile infection have significantly increased. This paper summarizes relevant researches， guidelines and consensuses at home and abroad， and elaborates the diagnosis and treatment of C. difficile infection in children from the aspects of epidemiology， risk factors，clinical features， and prevention and control measures.

Key words: Clostridium difficile, diagnosis, fecal microbiota transplantation, pediatric population